ZOPICLONE 7.5MG TABLETS FOR ANXIETY
Zopiclone 7.5mg is an effective & widely used sleeping tablets in treating sleep disorders, especially short-term insomnia. It belongs to a class of drugs called cyclopyrrolones. Zopiclone is a non-benzodiazepine hypnotic agent which has an instant mechanism for relaxing brain cells and inducing sleep within minutes of ingestion. Zopiclone tablets are beneficial sleeping tablet to attain quality slumber that can last for a longer period of time. Zopiclone sleeping tablets are merchandised under the renowned brand name of Imovane, Zimovane, and Datolan worldwide.
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ADDITIONAL INFORMATION ON ZOPICLONE SLEEPING TABLETS
We do care for our customer's health. Hence, we do not want any aspect of the medication to remain unfolded. Therefore, we recommend the users not to take the Zopiclone without consulting a physician. This medication is meant for short-term use and can be continued for about 3-4 weeks. We advise not to use the medication for so long as you may develop the tolerance and the medicine may seem less effective.
A Case Study On Zopiclone pills
A comprehensive study was conducted on a large group of insomnia patients (20,513 to be exact).
Untreated Condition of the Patients
On proper diagnosis, most of the insomniac patients showed at least one out of the following symptoms:
- Latency in sleep onset for more than an hour.
- Complains of tiredness on rising from sleep.
- Frequent awakening during the entire night and early arousal than the scheduled time.
- Complete nocturnal sleeping behavior with no somnolence the entire night.
- Total sleep time of fewer than 4 hours.
Post-treatment of the Patients with Zopiclone
The same patients have prescribed dosages of Zopiclone Pills before bedtime. The condition of the patients was observed over the span of 21 days and the following changes were reported:
- Approximately 87% of patients who were on the dosage of 7.5 mg were observed to have longer sleep cycles (at least 7-8 hours)
- The fatigue factor on waking up from sleep totally disappeared.
- Around 10 % of patients were suffering from a less severe stage of insomnia and were prescribed a mild dose of 3.75 mg of Zopiclone tablets per day. Almost, all these patients showed substantial improvement in their sleep-wake cycles and could restore a balanced level of somnolence.
Only a marginal ratio of 2.8 % of patients was reported to be not reacting positively to the consumption of Zopiclone tablets due to a multitude of reasons regarding their medical history. Apart from this slim ratio of patients, more than 97% of the insomnia patients reacted positively to Zopiclone tablets.
A right zopiclone dose can eliminate your insomnia, especially insomnia. But, it should be taken in the following directions:
- Zopiclone pills are recommended only when an individual can be affected by any sleep disorder.
- Zopiclone tablets can be the best sleeping tablets if the individual slumbers properly for the prescribed hours.
- Zopiclone gives you a sleeping slot for at least 7 to 8 hours.
- Zopiclone kicks into the system within one hour, so try to take a dose of 7.5 mg Zopiclone an hour before your bedtime.
- Zopiclone is usually prescribed for just 2 to 4 weeks. This is because your body gets used to it quickly, and after this time it's unlikely to have the same effect.
Zopiclone 7.5 mg is the prescribed dose (1 Tablet a Day) and it should not be exceeded to avoid any side effects. Zopiclone sleeping tablets should be swallowed as a whole with a glass of water before going to bed.
Note: Zopiclone 7.5 mg is a strong sleeping tablet and it is recommended to consult a physician before taking these sleeping pills.
ZOPICLONE SIDE EFFECTS
This is a sleeping tablet. Usually, all sleeping tablets will side effects by the next day itself. For example, after wake up, you may feel headaches, drowsiness, and giddiness. The general effects are a dry mouth, cause to feel the metallic taste and feeling sleepy in the day time also. It causes me to feel tired every time. It makes you feel lazy. Zipiclone's side effects are countable. Of course, it is low and affects less. It happens once in hundreds of people. Those are mentioned above lines. In this pill, serious effects also there. They are amnesia, hallucinations, and fall over, delusions, and feel depressed.
Not everyone will get side effects with Zopiclone. These common side effects happen in more than 1 in 100 people. Talk to your doctor or pharmacist if these side effects bother you or don’t go away:
- A bitter or metallic taste in your mouth or a dry mouth.
- Daytime sleepiness.
You should avoid the dosage of Zopiclone Tablets if your condition relates to any of the following points:
- Zopiclone can be taken by adults over the age of 18.
- If you have had an allergic reaction to Zopiclone or any other medicines in the past.
- If you have liver or kidney problems.
- You have breathing problems or sleep apnoea disorder.
- You having issues with alcoholism or drug abuse.
- If you are trying to get pregnant, are already pregnant.
- If you are breastfeeding.
- Never take 2 doses at the same time.
- Never take an extra dose to make up for a forgotten one.
The main aspect of the present invention is to provide a novel process for the preparation of EsZopiclone.
Another aspect of the present invention is to provide a process for the preparation of enantiomerically enriched isomer of EsZopiclone with chiral purity of about 95 to 99.5%
Yet another aspect of the present invention is to provide a process for the resolution of racemic Zopiclone to give EsZopiclone with improved yield. A further aspect of the present invention is to provide improved process for the preparation of Zopiclone.
U.S. Pat. NO. 3,862,149 patent discloses the process for the preparation of Zopiclone, wherein 6-(5-chloropyridin-2-yl)-5-hydroxy-7-oxo-5,6-dihydro pyrrolo-[3,4-b]-pyrazine is condensed with 1-chlorocarbonyl-4-methyl-piperazine in the presence of strong base such as sodium hydride in dimethylformamide to give Zopiclone.
For detailed patent info you can visit: https://patents.google.com/patent/US8309723B2/en
Q1: How will I know if this drug is approved for my sleep disorder and how should I take it?
A1: A generic form of Zopiclone is approved and endorsed by FDA for patients who suffer from bad bouts of insomnia and experience difficulty in attaining a sound sleep at night. A daily dose of 7.5 mg of Zopiclone should be taken before retiring to bed.
Q2: What are the active and inactive ingredients?
A2: Active Ingredient — Zopiclone Inactive ingredients — Calcium hydrogen phosphate, lactose, starch wheat, sodium starch glycollate, magnesium stearate, hypromellose, titanium dioxide, and macrogol.
Q3: How long does the effect stay?
A3: Zopiclone has a half-life of about 7-9 hours which means that it totally clears out of your system in 18 hours.
Q4: Is there any major side-effect I should be concerned about?
A4: Nausea, heartburn, vision impairment, agitation, changes in appetite, impotence, confusion, sleepwalking and agitation are some of the adverse side effects which should be reported to a doctor.
Q5: Is there any drug interaction possible?
A5: Zopiclone may interact with strong painkillers, sedatives, tranquillizers, antihistamines, antibiotics and muscle relaxants.
Q6: How should I store the medicine?
A6: Store the medicine in a cool dry place where the temperature stays below 25 degree Celsius. Keep the tablets in the blister form until it is time to use them.
Q7: How long does zopiclone take to work
A7: The zopiclone takes one hour completely to work. Mostly this medicine is prescribed for only two to four weeks by the doctor. For this reason, only you feel quickly, and at the same time, you have equal side effects. There are some serious side effects by coming slowly. If anyone took alcohol before taking the pill may cause you for losing your soul.